EHMN 2026 · model available on request
Thermodynamically refined SBML human metabolic network
EHMN 2026 is a modernised update of the Edinburgh Human Metabolic Network, designed as a reproducible genome-scale metabolic backbone for QSP integration and multi-layer modelling.
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11compartments
14,321SBML species
22,642reactions
3,996gene products
What it is
EHMN 2026 combines MetaNetX and ChEBI identifier harmonisation, duplicate reaction consolidation, thermodynamic directionality refinement, Reactome pathway annotation and SBML Level 3/FBC2 encoding.
- Constraint-based analysis backbone
- Gene-protein-reaction representation
- Reactome pathway organisation
- Thermodynamic cycle elimination
- QSP and multi-omics integration substrate
Access boundary
The paper is open access. Model files and associated support are available on request through IQANOVA, with release terms depending on use case, licence and collaboration route.
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